TitleCharacteristics of regenerated cartilage tissue cultured under traction loading
SourceMITC2015-pp 58-59
AuthorK. Fukuda, S. Omata, T. Yamaguchi, Y. Sawae


In this study, chondrocytes isolated from metacarpal-phalangeal joints were seeded in agarose gel. And, traction loading was applied to the surface of the gel by the roller to examine the effect of the tribological stimulation on the characteristics of the regenerated cartilage tissue elaborated in chondrocyteagarose construct. Results indicated that the traction loading enhanced ECM biosynthesis in the surface region selectively and subsequently elaborated tissue had anisotropic structure with collagen rich surface layer covered with GAG rich superficial layer.


MITC2015-pp 58-59